Objective: Dengue fever is one of the most common arboviral mediated outbreaks reported with increased prevalence year after year with considerable morbidity and mortality. This study was designed to assess the clinical and biochemical parameters of dengue fever patients.
Methods: Prospective observational study was undertaken among adult patients in a territory hospital. Two hundred patients were studied and analysed. All patients who were NS1 antigen/IgM dengue positive were included in the study. Clinical features, haematological and biochemical parameters were noted.
Results: Out of 200 patients admitted in Dr. PSIMS & RF, fever is the main constitutional symptom followed by headache, myalgias, pain abdomen, vomiting, rash and bleeding manifestations. About 92 patients presented with complications. Haematological and biochemical derangements were seen in about 80% of patients.
Conclusion: Dengue disease continues to involve newer areas, newer population and is increasing in magnitude, epidemic after epidemic. Dengvaxia(R) is a live attenuated tetravalent vaccine that is currently under evaluation and the vector control measures are also inadequate. Though clinical studies have reported on dengue disease in India, but these are largely based on diagnosis made by kits of doubtful specificity and sensitivity. A lot more remains to be achieved for creating an impact.
Impact Factor
2022: 6.012
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