Varicella zoster virus routine vaccination: need of the hour in endemic states of india

Author: 
Sana Irfan, RK Mahato, AAC Srivastava, Piyalee Gupta, Rita Chouhan, Manoj Kumar, Sahir Paul, Md Asad, Sushir Tiwari, Tarun Kumar Kar and N.Roopa

Purpose: Primary infection with Varicella Zoster virus (VZV) leads to Varicella or chickenpox. The epidemiology of Varicella has changed dramatically since the introduction of the Varicella vaccine in 1995. The routine childhood immunization in few countries of the western world like Germany and the United States had reduced the incidence of the disease, associated complications, hospital admissions and deaths related to its complications. However, chickenpox outbreaks are common in naive unvaccinated communities in India. Materials and Methods: We had investigated many outbreaks of chickenpox and reported in different areas of East Singhbhum in Kolhan region of Jharkhand during January 2018 to March 2019. The outbreak was confirmed with the detection of VZV IgM by enzyme-linked immunosorbent assay (ELISA) in serum samples from the patients. Results: A total of 76 suspected cases was collected in the outbreaks in which 45 number of serum samples showed positive serology for VZV IgM antibodies .Conclusions: There is an urgent need to identify naive communities and unvaccinated individuals at risk. Also, there is a need for regular training programmes of health workers posted in peripheral centres so that highly contagious communicable diseases can be picked up in time and such outbreaks can be prevented.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2019.3884.19971
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