Study of hypoglycemia in patients on maintenance hemodialysis

Author: 
Hariprasad., Gangadhar and Bhanu Prasad

The dialysate glucose concentration was as high as 1800 mg/dL. At that time, osmotic ultrafiltration (with sodium and glucose being the major osmoles) was the major mode of volume removal.1,2 Over time, ultrafiltration by hydrostatic pressure was found to be superior to osmotic ultrafiltration and the concentration of glucose in dialysate was drastically decreased. Subsequently, it became less clear what the ideal concentration of glucose should be in the dialysate. Many units switched to a glucose-free dialysate.
The study was done in maintenance hemodialysis unit of Gandhi Hospital,
Secunderabad over a period of one year from December 2013-December 2014. 50
patients were chosen by random sampling, 25 of them were diabetics and 25
non-diabetics.
Hypoglycemia is not uncommon (26%) in CKD V patients on maintenance hemodialysis, both in diabetics and nondiabetics.Incidence of hypoglycemia is more in diabetics than in nondiabetics, both with glucose-free hemodialysis solution and glucose-added hemodialysis solution.There was a decrease in the occurrence of hypoglycemia when glucose-added hemodialysis solution is used, both in diabetics and nondiabetics. Asymptomatic hypoglycemia is very common, both in diabetics and nondiabetics.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2018.9551.1583
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