A study on clinical forms of oral leukoplakia with grades of oral epithelial dysplasia

Swati Dahiya and Kondajji Ramchandra Vijayalakshmi

Background & Objectives: Oral Leukoplakia (OL) has multifactorial etiology with tobacco being the major etiological factor. The management of the oral leukoplakia poses a challenge as it relies on its clinical presentation and histopathological grading. Hence, the study was aimed tostudy the clinical forms and histological grades of oral leukoplakia associated with habit of tobacco.
Methods: 60 cases of oral leukoplakia were selected according to selection criteria and were subjected to incisional biopsy, followed by histopathological grading. The obtained values of these parameters were tabulated, statistically analyzed and observations were drawn.
Results: Non-homogenous leukoplakia was significantly associated with moderate epithelial dysplasia and whereas homogenous form was significantly associated with mild dysplasia (p value <.05). Also, statistically significant association was noted between tobacco & alcohol with moderate grade of dysplasia ( p value <.001)
Conclusions: This study suggests that severity of the clinical appearance of lesion is indicative of higher grade of epithelial dysplasia.

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DOI: http://dx.doi.org/10.24327/ijcar.2017.7222.1103
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