Structural elucidation of chemical compounds of pharmacological significance from convolvulus pluricaulis by gas chromatography: mass spectroscopy (gc-ms) analysis

Author: 
Manjushree Kundlik Pawar, Jayesh Ashok Dwivedi and Udichi Kataria Dwivedi

Background: Convolvulus Pluricaulis (CP) is a well-known ethnopharmacological herb in Ayurveda and exhibits a comprehensive range of therapeutic potential. Objective: The main objective of this research was to study the phytochemical profile of ethanolic extract of CP by Gas Chromatography Liquid Chromatography (GC-MS) analysis and to review the pharmacological activities associated with the compounds identified in this study from the literature. Materials and Methods: Ethanolic extract of CP was prepared by soxhlet extraction and the extract was subjected to GC-MS analysis (Agilent 7890A GC System) for chemical characterization of the extract. Results: The constituents were analysed by matching mass spectra with MS libraries. Total 19 different compounds were identified for CP extract belonging to different chemical groups like fatty acids, alkaloid, triterpenoid, diterpenoids, tetracycline antibiotic, cardiac glycoside and long chain aldehyde chemical group. The constituents of pharmacological significance include demeclocycline; n-hexadecanoic acid; hexadecanoic acid, ethyl ester; phytol; squalene; digitoxin; ethyl iso-allocholate; 9,12-octadecadienoic acid; 9,12,15-octadecatrienoic acid; Octadecanal 2-bromo; pentadecanoic acid, 14-methyl, methyl ester and 9,12,15- octadecatrienoic acid, 2-phenyl-1,3-dioxan-5-yl ester. Conclusion: The GC-MS analysis was successful in identifying the pharmacologically important phytochemicals and the eluted compounds could provide the researchers to work with different pharmacological activities related models and studies.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2023.2226.1485
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