Role of caspases in inflammatory responses

Author: 
Jinny Tomar

The role of inflammasomes has been very crucial in the process of survival both in terms of stress and infection for a cell. Inflammatory responses have been found to be dependent on the activation of inflammatory caspases, with the release of certain cell specific cytokines at different stages of infection. This review paper has tried to illustrate the role of caspases in inflammation, be it in the inflammasomal complex or the choice of inflammatory pathway adapted for a specific kind of stress induced in a cell due to infection, injury, auto immune disorders. Being a major part of pyroptosis, Inflammatory caspases have been identified as one of the potential target for therapeutic in case of a number of infections and cell immune related issues.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2020.22367.4408
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