Pulmonary alveolar microlithiasis with bronchial asthma

Pulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive disorder characterized by intra-alveolar accumulation of spherical microliths in the absence of any known calcium metabolism disorder. The hallmark of this disorder is clinical-radiological dissociation, meaning that there is a paucity of symptoms in contrast to characteristic imaging findings. At diagnosis, most patients are asymptomatic and changes in the lung parenchyma are found incidentally. As the disease advances patient may develop dyspnea, dry cough, chest pain. There are less than 1050 cases of PAM reported worldwide. We report a rare case of PAM with bronchial asthma.