A prospective study of prevalence of febrile nonhemolytic transfusion reactions due to different blood components in a tertiary care hospital

Author: 
Vinod Agarwal, Shantipriya Bhardwaj, Devraj Arya and Arun Bharti

Introduction: Febrile nonhemolytic transfusion reactions (FNHTRs) are characterized by
Fever (≥1°C elevation) that may be accompanied by chills, rigors, hypertension, tachycardia, and dyspnoea without another clinical explanation.
Aim: To analyse the incidence rate of FNHTR due to transfusion of different types of blood components and improve patient care and safety.
Material and Methods: A prospective study of transfusion reactions was conducted between August 2017 to November 2018 at the Blood Bank attached with department of
Transfusion Medicine at Sardar Patel Medical College & Associated Group of Hospitals, Bikaner (RAJ.).
Observations and Results:A total of 60967 units of blood components were issued to patients during the study period. 40346 units of PRBCs units were transfused and out of
which 1853 were prestorage leukoreduced and 38493units were non- leukoreduced PRBC. A total of 16 transfusion reactions were classified as FNHTRs.
Conclusion: The reduction of FNHTRs is supporting the use of prestorage leukoreduction of PRBCs and has a legitimate role to play in clinical transfusion practice. The rate of FNHTRs to allogenic PRBC units after the implementation of prestorage leukoreduction has decreased significantly.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2019.17405.3300
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