Prevalence of serum 25-hydroxy vitamin d deficiency and its influence on outcome in critically ill patients

Author: 
Kolathu Parambil Radhika., Balakrishnan Valliyot., Mubarak K.K and Melveetil S. Sreejit

Limited studies are available on vitamin D deficiency and its outcome in critically ill Indian population. We aimed to evaluate the prevalence of vitamin D deficiency and outcome like prolonged hospital stay and mortality.
Methods: In this observational study, thirty patients were included. Demographic profile and clinical parameters were noted. Blood samples (2ml) were collected for vitamin D estimation on admission. Patients were categorized into Deficient (Group D <30ng /ml) and Sufficient (Group S >30 ng /ml) groups. Patients were followed up for a period of 2 weeks or till discharge. Outcome noted were total hospital days and mortality.
Results: Vitamin D deficiency was present in 86.6% critically ill patients. A Negative correlation (Pearson Correlation - 0.01) was noted between vitamin D deficiency and total hospital days. Statistically no significant association was found between vitamin D deficiency and total hospital days (p =0.95). Mortality was found to be higher (66.7%) in vitamin D deficient patients than in vitamin D sufficient patients (33.3%).
Conclusion: Statistically significant association was not seen between vitamin D deficiency and adverse outcome like total hospital days and mortality. An inverse relation was noted between vitamin D deficiency and total hospital days.

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DOI: http://dx.doi.org/10.24327/ijcar.2017.8154.1300