Neuromyelitis optica

Author: 
Tikal Kansara

Background: Neuromyelitis Optica (NMO), also known as Devic’s disease, is an inflammatory condition of young females leading to demyelination especially of the optic nerve (ON) and spinal cord. Clinical features vary too widely that they form neuromyelitis disease spectrum. Some consider it to be a variant of multiple sclerosis (MS). It is caused by autoantibodies against aquaporin 4 (APQ4) channels. As a result, NMO is considered as an autoimmune disease.
Objective: To describe a patient which satisfied clinical criteria for NMO, however, lacked the laboratory confirmation of aquaporin autoantibodies.
Methods: Detailed history, physical examination and laboratory investigations.
Conclusion: As NMO has a disastrous clinical course, early identification of this disease is necessary, as with the possible treatment like rituximab, clinical course can be altered and the progression hampered.

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DOI: 
DOI: http://dx.doi.org/10.24327/ijcar.2017.3561.0314