Low doses of amisulpride and its side effects in treating schizophrenia

Amisulpride , the antipsychotic drug is claimed to be effective in both positive and negative symptoms of schizophrenia and related disorders. It has less to no action on serotonergic receptors. Limbic selectivity and lower striatal dopaminergic receptor binding capacity causes very low incidence of extra pyramidal side effects. But in clinical cases extra pyramidal side effects are seen even in lower doses in Indian context. More research on low doses of amisulpride and its side effects is required in India to find out the association.