Isolation and characterization of polymer from tamarind seed: an emerging excipient for pharmaceutical use

Author: 
Namrata Mohite, Pranali Salunkhe, Charushila Shinde, and Sayali Chavan

Background: To prepare and characterize the polymer from tamarind seed.
Material and Methods: Tamarind Seed Polymer extracted by water extraction method
Results: It has been observed that isolated tamarind seed polysaccharide shown acceptable properties for pharmaceutical formulations. Swelling index of isolated polysaccharide was found to be 1700%, the swelling property described high swelling ability of tamarind seed polysaccharide. High swelling of polymer will retard the drug release. So it can be used in formulations for controlled drug delivery system.
Conclusion: It was found that polysaccharide can be successfully isolated from tamarind seed using water based extraction procedure. Extracted polysaccharide has properties to be used as pharmaceutical excipient. It was also predicted from the study that extracted polysaccharide can be used as a gelling agent, binder etc. in different pharmaceutical preparations.

Download PDF: 
DOI: 
http://dx.doi.org/10.24327/ijcar.2019.19027.3652
Select Volume: 
Volume8