Evaluation of retinal nerve fiber layer thickness and optic nerve head parameter in migraine as a risk factor in open angle glaucoma

Author: 
Masitha Dewi Sari., Aryani A Amra and Vanda Virgayanti

Background: Migraine is a primary debilitating headache disorder with common neurolological signs. Variations in optic nerve perfusions quality or retinal microcirculation may end up in ganglion cell damage in patients with migraine
Methods: A prospective, analytical observational with cross sectional study was conducted at the Adam Malik Hospital from January 2016 to July 2016 after approved by the Ethics Committee for Health Research Sumatera Utara University School of MedicineThirty seven patients diagnosed with migraine divided two groups as migraine without aura and migraine with aura were evaluated. Retinal nerve fiber layer (RNFL) thickness and Optc Nerve Head (ONH) was measured by using Cirrus Optical Coherence Tomography (OCT)
Results: RNFL became thinner and ONH became enlargement in several patients with migraine but not significantly differences in all quadrant between the two groups. There was significantly differences the risk of open angle glaucoma between the two groups, wheres seven migraine without aura patients and ten migraine with aura patients got normal tension glaucoma (NTG) (p<0,05).
Conclusion: Normal Tension Glaucoma (NTG) is a risk factor in migraine and the retinal blood flow decreased theory might be able to defend

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DOI: 
DOI: http://dx.doi.org/10.24327/ijcar.2017.3967.0407