Evaluation of efficacy of concentrated growth factor (cgf) biomaterial in the treatment of intrabony defects –a randomized clinical trial

Author: 
Beanish Bashir., Suhail Majid Jan., Roobel Behal., Reyaz Ahmed Mir and Syed Saima

Aim: To document the beneficial role of CGF as an adjunct to open flap debridement (OFD) in treatment of intrabony defects in chronic periodontitis patients.
Materials and Methods: 20 intrabony defects in 20 patients were randomly divided into 2 groups and were treated with OFD (group A) or CGF +OFD (group B). Clinical parameters such as plaque index (PI), probing depth (PD), relative attachment level (RAL) and the hard tissue parameter Alveolar crest to the base of the defect (AC-BOD) were assessed at baseline and 9 months postoperatively.
Results: Statistically significant intra group improvements were seen with all the hard tissue and soft tissue parameters in both test and control groups. Statistically significant improvements were seen with the mean defect fill (AC-BOD) when intergroup comparisons were made.
Conclusions: The study demonstrated that CGF improves clinical and radiological parameters compared to OFD alone in intrabony defects.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2019.17622.3348
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