Diagnostic and therapeutic strategy in the management of differentiated thyroid carcinomas: about 32 cases

Hicham Attifi., Mohammed Sina., Mounir Hmidi., Karim Nadour., Ali Elboukhari and Mohammed Zalagh

The differentiated thyroid carcinoma is the most common endocrine cancer. Its incidence is increasing in most countries including Morocco. Our work was a retrospective study of 32 DTC’s cases, gathered from 630 thyroid surgical gestures in the ENT department of Military Hospital Moulay Ismail of Meknes, over 8 years from January 2007 to December 2014. The aim of our study was to expose different epidemiological, diagnostic, therapeutic and evolutionary aspects of DTC. Our series included 21 women and 11 men. Thyroid nodule was the main reason of consultation (90.5%). On ultrasound, the nodules were respectively solid and hypoechoic in 78% and 82% of cases. We respectively performed a total and partial thyroidectomy totalized after final histological examination in 34.37% and 65.63 % of cases, which we respectively associated to central and lateral neck dissection in 62.62% and 21.87% of cases. The final histological examination respectively revealed papillary and vesicular carcinoma in 81.25% and 18.75% of cases. Lymph node involvement was found in 28.12% of cases. Radioiodine remnant ablation interested 66% patients. Three cases of lymph node recurrence were detected. There is a need of standardized diagnostic and therapeutic strategy with a view of an appropriate management of DTC.

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DOI: http://dx.doi.org/10.24327/ijcar.2017.4369.0501