Comparative evaluation of serum transaminases and serum creatinine in smokers and non smokers with periodontitis

Author: 
Naga Sri M*., Asha Latha J, Svvs Musalaiah., Aravind Kumar P., Indeevar P and Ravi Raj K

Background: Periodontitis is an inflammatory disease of periodontal structures which was influenced by several factors like smoking and systemic disorders. Smoking impairs the immune response and compromises the periodontal tissue health following a period of disease activity. Systemic disorders like renal and liver malfunctioning also alters the immune responses in the body.
Aim: To compare and evaluate the levels of serum transaminases and serum creatinine in smokers and non smokers before and after Scaling and Root planing (SRP).
Materials and methods: 20 subjects were assigned into 2 groups, Group A (nonsmokers), Group B (smokers). All clinical parameters, biochemical parameters (serum transaminases & serum creatinine) levels were evaluated at baseline and 3 months after SRP.
Results: The present study showed a significant reduction in mean values of serum transaminases and increase in serum creatinine in both the groups with a greater reduction of transaminases and increase in creatinine in group A compared to group B.
Conclusion: Transaminases showed a direct relationship and creatinine showed an inverse relationship with periodontitis.

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DOI: 
DOI: http://dx.doi.org/10.24327/ijcar.2017.4873.0602