Clinical profile of patients with thrombocytopenia at a tertiary care centre

Nithyalakshmi Gaudam., Sandhya and Palaniandavan S

Introduction: Thrombocytopenia is a common finding in clinical practice. There are various reasons for the development of thrombocytopenia.The underlying cause may be either inconsequential or life threatening.
Aims & Objectives: To evaluate various causes of thrombocytopenia and to study the clinical profile and laboratory parameters in patients with thrombocytopenia. Materials and Method: A total of 200 patients with thrombocytopenia admitted to Sree Balaji Medical College and Hospital were evaluated. Patients with platelet count <1 lack/mm3 were included in study whereas patients with malignancy and chemotherapy induced thrombocytopenia were excluded.
Results: The present study includes patients between18-70 years of age. The highest incidence of thrombocytopenia belonged to the age group 21-30 years (30%) followed by 18-20 years (24%) and 31-40 years (22%). Diseases causing thrombocytopenia such as, megaloblastic anemia and infections (malaria, dengue, enteric fever, and septicemia) were found to be common in younger population. In our study, majority of the patients belonged to age group of younger than 40 years.
Conclusion: Major cause of thrombocytopenia was found to be due to dengue fever. Bleeding manifestations were noted in one-third of the population.

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