Study of serum lipids in severe falciparum malaria

Author: 
Dr. Vishal Yadav

Background and Objectives: Malaria is a potentially life threatening disease, which is transmitted by the infectious bite of the female Anopheles mosquito. In India, malaria is a major public health problem. Various studies have found that hypocholesterolemia and hypertriglyceridemia correlate with the severity of falciparum malaria.
This study intends to find a relationship between serum cholesterol and serum triglycerides done before initiating treatment and the severity of falciparum malaria.
Material and Methods: A total of 50 patients who had one or more of the features of severe malaria were selected and random serum cholesterol and serum triglycerides were sent prior to initiation of treatment .different parameters were compared with other similar studies. Results: All patients with severe falciparum malaria had low serum cholesterol levels. Seventy percent of patients had elevated serum triglyceride levels.
Elevated triglycerides were also associated with elevated levels of serum creatinine in these patients. A low random blood sugar correlated with a low cholesterol level in study population.
Conclusions: This study illustrates the significant impact of severe falciparum malaria on common lipid values in adults.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2020.22399.4414
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