Role of cytokines in inflammatory diseases

Valli B and M.Sankari

Cytokines are small secreted proteins released by cells have a specific effect on the interactions and communications between cells. Cytokine is a general name; other names are lymphokine, monokine, chemokine, and interleukin. Cytokines may act on the cells that secrete them), on nearby cells, or in some instances on distant cells. There are both pro-inflammatory cytokines and anti-inflammatory cytokines. There is significant evidence showing that certain cytokines/chemokines are involved in not only the initiation but also the persistence of pathologic pain by directly activating nociceptive sensory neurons.

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