Potential use of hydrazine carbothioamide in the synthesis of hetrocyclic moieties

Rashidi N.A

The condensation of different substituted acid hydrazides (a-g) with t-butyl isothiocyanate gave N-tert-butyl-2-aroyl hydrazine carbothioamides (IIa-g). The intramolecular cyclization of substituted hydrazine carbothioamide (Ia-g) under different condition furnished 1,2,4-triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole. The structures of all the synthesized compounds were established on the basis of IR, H1- NMR, Mass and elemental analysis.

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DOI: http://dx.doi.org/10.24327/ijcar.2017.8079.1284