Mycobacterial bacilli in formalin-fixed, paraffin-embedded breast tissue specimens of patients histologically diagnosed with breast carcinoma

Author: 
*Oyero S.K., Onwuliri F.C., Abdulkadir B., Itelima J.U and Dakwom Nanbam G

Tuberculosiss (TB) of breast, caused by Mycobacterium tuberculosis, is a rare disease and often mimics breast cancer. The smallness and paucity of tubercle bacilli in the tissue section make it very arduous and time-consuming to search for them in stained tissue sections. This present study was performed to investigate the usefulness of acid-fast bacilli (AFB) staining in determining breast tuberculosis in breast biopsy specimens of patients histologically diagnosed with breast carcinoma (Bca). Ziehl-Neelsen staining was done for acid-fast bacilli on 333 formalin-fixed, paraffin embedded sections of breast tissue blocks. Mycobacterial tubercle bacilli were seen in only 2 (0.6%) of the 333 specimens. This study reveals that the Ziehl Neelson stain can be a valuable tool in diagnosing extrapumonary TB in formalin-fixed, paraffin-embedded specimens.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2021.24496.4860
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