Demographic and clinical profile of kidney donors

Over the years it has been observed that there is a predominance of female to male donations in living donor (LD) kidney transplantation. Factors like age, gender, familial predisposition influence donors renal function and hence the outcome of renal transplant recipient [2]. In a resource limited setting like India, it is important to understand the risk involved in renal donation. Our present study aims to outline the demographic profile and post operative followup in terms of proteinuria, hypertension and serum creatinine at 1 , 3 and 6 months of nephrectomy .
We observed a significant increase in the amount of volunteer renal donations almost doubling every year. Majority (78%) of the donors were females while males contributed to 21.8 % of renal donations . We observed that mothers contributed to be the highest number of donors accounting for 181 donations (n=600) followed by wives which contributed to 102 of renal donors (n=600) , 98 ( 16.3%) fathers donated to their children .
We observed a rise of 9.66 mmHg in MAP (mean arterial pressure) (p<0.05). In our study, we found hypertension in 55 post-nephrectomy(p<0.05) at 6 months followup . 50 % of donors who had family history of hypertension, became hypertensive.
None of the donors had microalbuminuria prenephrectomy, none of the donors developed proteinuria on followup at 1, 3 and 6 months. None of the donors had mortality at 6 months followup.
This study highlights the demographic characteristics and clinical profile of renal donors from a tertiary care center in a developing nation.