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Enterococci are considered to be important nosocomial pathogen and its intrinsic property of antibiotic resistance made treatment difficult. Hence a preliminary study was conducted on the prevalence of Enterococcal infections and its antibiotic sensitivity pattern in Sunrise Institute of Medical Sciences, a tertiary care hospital at Kochi. Various clinical specimens like blood, urine, abscess, vaginal swab etc. were analyzed and a total of 93 isolates were obtained. Four species like E.faecalis, E.faecium, E.raffinosus and E.avium were isolated and 38 % of total isolates were multi drug resistant strains.