Background: The study aimed to compare the postoperative analgesic efficacy and safety profile of epidural Ropivacaine versus a combination of Ropivacaine and Tramadol in patients undergoing abdominal surgeries under general anesthesia. Methods: A total of 60 patients were randomized into two groups: Group 1 (Ropivacaine alone) and Group 2 (Ropivacaine with Tramadol). The primary outcomes were the duration of postoperative analgesia, sedation levels, and adverse effects. The Ramsay Sedation Score (RSS) was used to assess sedation, while adverse effects such as nausea, vomiting, and pruritus were recorded. The statistical significance of differences between the two groups was analyzed using unpaired t-tests. Results: The mean duration of postoperative analgesia was significantly longer in the Ropivacaine with Tramadol group (309.90 minutes) compared to the Ropivacaine alone group (220.57 minutes) (p < 0.0001). The Ramsay Sedation Score was higher in the Ropivacaine with Tramadol group (mean 3.06) compared to the Ropivacaine group (mean 1.26), indicating increased sedation (p < 0.0001). The incidence of postoperative nausea and vomiting (PONV) and pruritus was low in both groups, with no statistically significant difference (p > 0.05). Hemodynamic parameters were stable in both groups. Conclusion: The combination of Ropivacaine with Tramadol provides superior postoperative analgesia compared to Ropivacaine alone, with an extended analgesic duration and mild sedation. These findings suggest that Ropivacaine with Tramadol is a viable option for effective postoperative pain management in abdominal surgeries, with minimal adverse effects and stable hemodynamic parameters.
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2022: 6.012
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